PubMed referenced articles 1. Patient-derived fibroblasts indicate oxidative stress status and may justify antioxidant therapy in OXPHOS disorders. Voets AM, Lindsey PJ, Vanherle SJ, Timmer ED, Esseling JJ, Koopman WJ, Willems PH, Schoonderwoerd GC, De Groote D, Poll-The BT, de Coo IF, Smeets HJ. Biochim Biophys Acta. 2012 Jul 13;1817(11):1971-1978. 2. Effect of the Intake of Resveratrol, Resveratrol Phosphate, and Catechin-Rich Grape Seed Extract on Markers of Oxidative Stress and Gene Expression in Adult Obese Subjects. De Groote D, Van Belleghem K, Devière J, Van Brussel W, Mukaneza A, Amininejad L. Ann Nutr Metab. 2012 Jul 5;61(1):15-24. [Epub ahead of print] 3. Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis. Paquet P, De Groote D, Piérard GE. Dermatology. 2010;220(3):201-7. Epub 2010 Mar 23. 4. Effects of oral contraception with ethinylestradiol and drospirenone on oxidative stress in women 18-35 years old. De Groote D, Perrier d'Hauterive S, Pintiaux A, Balteau B, Gerday C, Claesen J, Foidart JM. Contraception. 2009 Aug;80(2):187-93. Epub 2009 Apr 22. 5. Monitoring of cellular responses after vaccination against tetanus toxoid: comparison of the measurement of IFN-gamma production by ELISA, ELISPOT, flow cytometry and real-time PCR. Tassignon J, Burny W, Dahmani S, Zhou L, Stordeur P, Byl B, De Groote D. J Immunol Methods. 2005 Oct 30;305(2):188-98. Epub 2005 Aug 31. 6. Immune monitoring in whole blood using real-time PCR. Stordeur P, Zhou L, Byl B, Brohet F, Burny W, de Groote D, van der Poll T, Goldman M. J Immunol Methods. 2003 May 1;276(1-2):69-77. 7. Synovial fluid matrix metalloproteinase-3 levels are increased in inflammatory arthritides whether erosive or not. Ribbens C, Andre B, Kaye O, Kaiser MJ, Bonnet V, Jaspar JM, de Groote D, Franchimont N, Malaise MG. Rheumatology (Oxford). 2000 Dec;39(12):1357-65. 8. Increased synovial fluid levels of interleukin-12, sCD25 and sTNF-RII/sTNF-RI ratio delineate a cytokine pattern characteristic of immune arthropathies. Ribbens C, André B, Kaye O, Kaiser MJ, Bonnet V, de Groote D, Franchimont N, Malaise MG. Eur Cytokine Netw. 2000 Dec;11(4):669-76. 9. Cytokine production from peripheral whole blood in atopic and nonatopic asthmatics: relationship with blood and sputum eosinophilia and serum IgE levels. Bettiol J, Bartsch P, Louis R, De Groote D, Gevaerts Y, Louis E, Malaise M. Allergy. 2000 Dec;55(12):1134-41. 10. Increased production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 by inflamed mucosa in inflammatory bowel disease. Louis E, Ribbens C, Godon A, Franchimont D, De Groote D, Hardy N, Boniver J, Belaiche J, Malaise M. Clin Exp Immunol. 2000 May;120(2):241-6. 11. Matrix metalloproteinase-3 serum levels are correlated with disease activity and predict clinical response in rheumatoid arthritis. Ribbens C, Andre B, Jaspar JM, Kaye O, Kaiser MJ, De Groote D, Malaise MG. J Rheumatol. 2000 Apr;27(4):888-93. 12. Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA). Ribbens C, Bonnet V, Kaiser MJ, Andre B, Kaye O, Franchimont N, de Groote D, Beguin Y, Malaise MG. Clin Exp Immunol. 2000 Apr;120(1):194-9. 13. Ex vivo interferon-gamma response to human immunodefiency virus-1 derived peptides in human immunodeficiency virus-1 infected patients. Hober D, Benyoucef S, Chehadeh W, De Groote D, De La Tribonnière X, Mouton Y, Wattré P. Scand J Immunol. 2000 Apr;51(4):429-33.
14. CD3 antibody-induced IL-10 in renal allograft recipients: an in vivo and in vitro analysis. Herbelin A, Abramowicz D, de Groote D, Naret C, Kreis H, Bach JF, Goldman M, Chatenoud L. Transplantation. 1999 Sep 15;68(5):616-22. 15. Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guérin vaccination. Marchant A, Goetghebuer T, Ota MO, Wolfe I, Ceesay SJ, De Groote D, Corrah T, Bennett S, Wheeler J, Huygen K, Aaby P, McAdam KP, Newport MJ. J Immunol. 1999 Aug 15;163(4):2249-55. 16. Specific immune response to human immunodeficiency virus (HIV)-1 in patients assessed through the production of interferon- gamma and interleukin-4 in HIV-1 p24-activated whole blood cultures: relationship with the viral load in plasma. Hober D, Benyoucef S, Chieux V, De Groote D, De La Tribonnière X, Bocket L, Lion G, Mouton Y, Wattré P. Scand J Immunol. 1999 Jul;50(1):83-90. 17. Soluble tumor necrosis factor receptor type II (sTNFRII) in HIV-infected patients: relationship with the plasma level of HIV-1 RNA. Hober D, Benyoucef S, Bocket L, Chieux V, Lion G, Mouton Y, De Groote D, Wattré P. Immunol Lett. 1999 Apr 1;67(2):91-4. 18. Soluble tumor necrosis factor receptors in chronic hepatitis C: a correlation with histological fibrosis and activity. Zylberberg H, Rimaniol AC, Pol S, Masson A, De Groote D, Berthelot P, Bach JF, Bréchot C, Zavala F. J Hepatol. 1999 Feb;30(2):185-91. 19. Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity. Menten P, Proost P, Struyf S, Van Coillie E, Put W, Lenaerts JP, Conings R, Jaspar JM, De Groote D, Billiau A, Opdenakker G, Van Damme J. Eur J Immunol. 1999 Feb;29(2):678-85. 20. Cellular vaccines. Bartholeyns J, Romet-Lemonne JL, Chokri M, Buyse M, Velu T, Bruyns C, Van de Winkel JJ, Heeney J, Koopman G, Malmsten M, De Groote D, Monsigny M, Midoux P, Alarcon B. Res Immunol. 1998 Sep-Oct;149(7-8):647-9. 21. Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Louis E, Franchimont D, Piron A, Gevaert Y, Schaaf-Lafontaine N, Roland S, Mahieu P, Malaise M, De Groote D, Louis R, Belaiche J. Clin Exp Immunol. 1998 Sep;113(3):401-6. 22. RANTES production in HIV-1 antigen-stimulated whole blood culture: relationship with type 1 immune response and plasma viral load in individuals infected with HIV-1. Benyoucef S, Hober D, De Groote D, Bocket L, De La Tribonnière X, Mouton Y, Wattré P. Scand J Immunol. 1998 Aug;48(2):212-6. 23. Inflammation: "a natural experiment" for the systemic pathogenicity of cytokines. Herbelin C, Roux-Lombard P, Herbelin A, Peuchmaur M, De Groote D, Griscelli C, Dayer JM, Prieur AM. Eur Cytokine Netw. 1998 Mar;9(1):57-60. 24. Effects of three avocado/soybean unsaponifiable mixtures on metalloproteinases, cytokines and prostaglandin E2 production by human articular chondrocytes. Henrotin YE, Labasse AH, Jaspar JM, De Groote DD, Zheng SX, Guillou GB, Reginster JY. Clin Rheumatol. 1998;17(1):31-9. 25. Imbalance in cytokine production by whole blood related to presence of cytopathogenic HIV-1 strains in HIV-1-infected patients. Benyoucef S, Lion G, Gérard Y, Wattré P, De Groote D, Hober D. Infection. 1998 Mar-Apr;26(2):109-12. 26. Effects of dexamethasone on the profile of cytokine secretion in human whole blood cell cultures. Franchimont D, Louis E, Dewe W, Martens H, Vrindts-Gevaert Y, De Groote D, Belaiche J, Geenen V. Regul Pept. 1998 Jan 2;73(1):59-65.
27. Tumor necrosis factor alpha levels in plasma and whole-blood culture in dengue-infected patients: relationship between virus detection and pre-existing specific antibodies. Hober D, Nguyen TL, Shen L, Ha DQ, Huong VT, Benyoucef S, Nguyen TH, Bui TM, Loan HK, Le BL, Bouzidi A, De Groote D, Drouet MT, Deubel V, Wattré P. J Med Virol. 1998 Mar;54(3):210-8. 28. Increased levels of leukaemia inhibitory factor (LIF) in urine and tissue culture supernatant from human primary bone tumours. Gouin F, Heymann D, Raher S, De Groote D, Passuti N, Daculsi G, Godard A. Cytokine. 1998 Feb;10(2):110-4. 29. A high serum concentration of interleukin-6 is predictive of relapse in quiescent Crohn's disease. Louis E, Belaiche J, van Kemseke C, Franchimont D, de Groote D, Gueenen V, Mary JY. Eur J Gastroenterol Hepatol. 1997 Oct;9(10):939-44. 30. Human monocytoid cell lines as indicators of endotoxin: comparison with rabbit pyrogen and Limulus amoebocyte lysate assay. Eperon S, De Groote D, Werner-Felmayer G, Jungi TW. J Immunol Methods. 1997 Sep 24;207(2):135-45. 31. Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10. Buelens C, Verhasselt V, De Groote D, Thielemans K, Goldman M, Willems F. Eur J Immunol. 1997 Aug;27(8):1848-52. 32. An interferon-gamma (IFN-gamma) based whole blood assay to detect T cell response to antigens in HIV-1 infected patients. Benyoucef S, Hober D, De Groote D, De La Tribonniere X, Vilain V, Lion G, Bouzidi A, Wattre P. Pathol Biol (Paris). 1997 May;45(5):400-3. 33. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. Verhasselt V, Buelens C, Willems F, De Groote D, Haeffner-Cavaillon N, Goldman M. J Immunol. 1997 Mar 15;158(6):2919-25. 34. Sepsis and serum cytokine concentrations. Damas P, Canivet JL, de Groote D, Vrindts Y, Albert A, Franchimont P, Lamy M. Crit Care Med. 1997 Mar;25(3):405-12. 35. Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor. Buelens C, Verhasselt V, De Groote D, Thielemans K, Goldman M, Willems F. Eur J Immunol. 1997 Mar;27(3):756-62. 36. Production of TNFalpha and IL-6 by activated whole blood from HIV-1 infected patients detected by a one-stage procedure: relationship with the phenotype of HIV-1 isolates. Benyoucef S, Hober D, Shen L, Ajana F, De Groote D, Bocket-Mouton L, Gérard Y, Lion G, Vilain V, Wattré P. Microbiol Immunol. 1997;41(12):939-46. 37. Increase in cytokine production (IL-1 beta, IL-6, TNF-alpha but not IFN-gamma, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis. Zheng SX, Vrindts Y, Lopez M, De Groote D, Zangerle PF, Collette J, Franchimont N, Geenen V, Albert A, Reginster JY. Maturitas. 1997 Jan;26(1):63-71. 38. Imbalance between IL-1 and IL-1 receptor antagonist in the cerebrospinal fluid of HIV-infected patients. Rimaniol AC, Zylberberg H, Rabian C, DeGroote D, Zavala F, Viard JP. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Dec 15;16(5):340-2. 39. Differential effects of interleukin-10 on the production of interleukin-12 and interleukin-8 by human dendritic cells generated from peripheral blood. Buelens C, De Groote D, Goldman M, Willems F. Transplant Proc. 1996 Dec;28(6):3255-6. No abstract available.
40. Cytokine production by human thymic epithelial cells: control by the immune recognition of the neurohypophysial self-antigen. Martens H, Malgrange B, Robert F, Charlet C, De Groote D, Heymann D, Godard A, Soulillou JP, Moonen G, Geenen V. Regul Pept. 1996 Nov 14;67(1):39-45. 41. Enhanced TNF alpha production by monocytic-like cells exposed to dengue virus antigens. Hober D, Shen L, Benyoucef S, De Groote D, Deubel V, Wattré P. Immunol Lett. 1996 Nov;53(2-3):115-20. 42. Characterization of monoclonal antibodies against human interleukin-12 and their use in an ELISA for the measurement of this cytokine. Fauchet F, Jadoul M, Franssen JD, Zhang J, De Groote D. Ann N Y Acad Sci. 1996 Oct 31;795:334-6. No abstract available. 43. Serum soluble CD23 levels in giant cell arteritis. Roblot P, Morel F, Lelièvre E, Biais-Sauvètre MH, de Groote D, Preud'homme JL, Lecron JC. Immunol Lett. 1996 Oct;53(1):41-4. 44. Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes. Henrotin YE, De Groote DD, Labasse AH, Gaspar SE, Zheng SX, Geenen VG, Reginster JY. Osteoarthritis Cartilage. 1996 Sep;4(3):163-73. 45. Plasma levels of sTNFR p75 and IL-8 in patients with HIV-1 infection. Hober D, Benyoucef S, Delannoy AS, De Groote D, Ajana F, Mouton Y, Wattré P. Immunol Lett. 1996 Aug;52(1):57-60. 46. Adenosine enhances IL-10 secretion by human monocytes. Le Moine O, Stordeur P, Schandené L, Marchant A, de Groote D, Goldman M, Devière J. J Immunol. 1996 Jun 1;156(11):4408-14. 47. High plasma level of soluble tumor necrosis factor receptor type II (sTNFRII) in asymptomatic HIV-1-infected patients. Hober D, Benyoucef S, Delannoy AS, de Groote D, Ajana F, Mouton Y, Wattré P. Infection. 1996 May-Jun;24(3):213-7. 48. TNF alpha production by whole blood from HIV-1 infected patients. Benyoucef S, Hober D, Shen L, Ajana F, De Groote D, Gérard Y, Lion G, Vermesch A, Bocket-Mouton L, Mouton Y, Wattré P. Pathol Biol (Paris). 1996 May;44(5):393-6. 49. Leukaemia inhibitory factor (LIF) production in pleural effusions: comparison with production of IL-4, IL-8, IL-10 and macrophage-colony stimulating factor (M-CSF). Heymann D, L'Her E, NGuyen JM, Raher S, Canfrère I, Coupey L, Fixe P, Chailleux E, De Groote D, Praloran V, Godard A. Cytokine. 1996 May;8(5):410-6. 50. Cuprophane haemodialysis induces upregulation of LPS receptor (CD14) on monocytes: role of complement activation. Marchant A, Tielemans C, Husson C, Gastaldello K, Schurmans T, De Groote D, Duchow J, Vanherweghem L, Goldman M. Nephrol Dial Transplant. 1996 Apr;11(4):657-62. 51. UVB-irradiation of human bone marrow: potential for donor specific tolerance. Noizat-Pirenne F, Greenfeld JI, Hardy MA, Oluwole SF, De Groote D, Franchimont P. J Surg Res. 1996 Feb 15;61(1):267-74. 52. Optimal control of interferon-gamma and tumor necrosis factor-alpha by interleukin-10 produced in response to one HLA-DR mismatch during the primary mixed lymphocyte reaction. Toungouz M, Denys C, de Groote D, Andrien M, Dupont E. Transplantation. 1996 Feb 15;61(3):497-502. 53. High levels of sTNFR p75 and TNF alpha in dengue-infected patients. Hober D, Delannoy AS, Benyoucef S, De Groote D, Wattré P. Microbiol Immunol. 1996;40(8):569-73. 54. Ex vivo cytokine production by whole blood cells from cancer patients. De Groote D, Gevaert Y, Lopez M, Gathy R, Marchal F, Detroz B, Jacquet N, Geenen V. Cancer Detect Prev. 1996;20(3):207-13.
55. Interleukin 12 unmasks HLA class I differences during mixed lymphocyte reaction induced interferon gamma production. Toungouz M, Denys C, Andrien M, De Groote D, Dupont E. Hum Immunol. 1995 Nov;44(3):145-55. 56. Role of defective monocyte interleukin-10 release in tumor necrosis factor-alpha overproduction in alcoholics cirrhosis. Le Moine O, Marchant A, De Groote D, Azar C, Goldman M, Devière J. Hepatology. 1995 Nov;22(5):1436-9. 57. Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor beta chain (IL-2R beta). Moreau JL, Bossus M, de Groote D, François C, Jacques Y, Tartar A, Thèze J. Mol Immunol. 1995 Oct;32(14-15):1047-56. 58. Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock. Marchant A, Alegre ML, Hakim A, Piérard G, Marécaux G, Friedman G, De Groote D, Kahn RJ, Vincent JL, Goldman M. J Clin Immunol. 1995 Sep;15(5):266-73. 59. Modulation of LIF expression in human melanoma cells by oncostatin M. Heymann D, Blanchard F, Raher S, De Groote D, Godard A. Immunol Lett. 1995 Jun;46(3):245-51. 60. In vivo soluble tumor necrosis factor receptor release in OKT3-treated patients. Differential regulation of TNF-sR55 and TNF- sR75. Herbelin A, Chatenoud L, Roux-Lombard P, De Groote D, Legendre C, Dayer JM, Descamps-Latscha B, Kreis H, Bach JF. Transplantation. 1995 May 27;59(10):1470-5. 61. In vitro inhibition of tumour necrosis factor-alpha and interleukin-6 production by intravenous immunoglobulins. Toungouz M, Denys CH, De Groote D, Dupont E. Br J Haematol. 1995 Apr;89(4):698-703. 62. Adverse effect of abdominal operations on production of interferon-gamma. Pirenne J, Ribbens C, Médot M, De Groote D, Vrindts Y, Lopez M, Gathy R, Franchimont P, Jacquet N. Eur J Surg. 1995 Feb;161(2):77-83. Review. 63. Balance between IL-1 beta, TNF-alpha, and their specific inhibitors in chronic renal failure and maintenance dialysis. Relationships with activation markers of T cells, B cells, and monocytes. Descamps-Latscha B, Herbelin A, Nguyen AT, Roux-Lombard P, Zingraff J, Moynot A, Verger C, Dahmane D, de Groote D, Jungers P, et al. J Immunol. 1995 Jan 15;154(2):882-92. 64. Increased plasma levels of human interleukin for DA1.a cells/leukemia inhibitory factor in sepsis correlate with shock and poor prognosis. Villers D, Dao T, Nguyen JM, Bironneau E, Godard A, Moreau M, De Groote D, Nicolas F, Soulillou JP, Anegon I. J Infect Dis. 1995 Jan;171(1):232-6. 65. Defective cytokine expression but adult-type T-cell receptor, CD8, and p56lck modulation in CD3- or CD2-activated T cells from neonates. Pirenne-Ansart H, Paillard F, De Groote D, Eljaafari A, Le Gac S, Blot P, Franchimont P, Vaquero C, Sterkers G. Pediatr Res. 1995 Jan;37(1):64-9. 66. Changes in bronchial responsiveness, circulating leucocytes and ex vivo cytokine production by blood monocytes after PAF inhalation in allergic asthmatics. Louis R, Degroote D, Bury T, Corhay JL, Kayembe JM, Franchimont P, Radermecker MF. Eur Respir J. 1995 Apr;8(4):611-8. 67. Biologic monitoring of the efficacy of immunosuppression in liver transplant patients. Farges O, Buffello D, Swercz B, deGroote D, Bismuth H. Transplant Proc. 1995 Aug;27(4):2516-8. No abstract available. 68. Changes in bronchial responsiveness, circulating leucocytes and ex vivo cytokine production by blood monocytes after PAF inhalation in allergic asthmatics. Louis R, Degroote D, Bury T, Corhay JL, Kayembe JM, Franchimont P, Radermecker MF.
Eur Respir J. 1995 Apr;8(4):611-8. 69. Balance between IL-1 beta, TNF-alpha, and their specific inhibitors in chronic renal failure and maintenance dialysis. Relationships with activation markers of T cells, B cells, and monocytes. Descamps-Latscha B, Herbelin A, Nguyen AT, Roux-Lombard P, Zingraff J, Moynot A, Verger C, Dahmane D, de Groote D, Jungers P, et al. J Immunol. 1995 Jan 15;154(2):882-92. 70. Biochemical identification of keratinocytes antigens recognized by anti-human interleukin-2 antibodies Sorel M , Cherel M , Francois C , Dreno B , Bouyge I , De Groote D , Minvielle S , Jacques Y Eur J Dermatol. 1995,5(8):720-727. 71. Characterisation of monoclonal antibodies against human interleukin-10 and their use in an ELISA for the measurement of this cytokine. De Groote D, Marchant A, Fauchet F, Jadoul M, Dehart I, Gérard C, Gevaert Y, Lopez M, Gathy R, Franssen JD, et al. J Immunol Methods. 1994 Dec 28;177(1-2):225-34. 72. Tumor necrosis factor-alpha and interleukin-6 production induced by variations of DR4 polymorphism during the primary mixed lymphocyte reaction. Toungouz M, Denys CH, Andrien ME, de Groote D, Dupont EC. Transplantation. 1994 Dec 27;58(12):1393-8. 73. Induction of soluble tumor necrosis factor receptor (sTNF-R75) release by HIV adsorption on cultured human monocytes. Rimaniol AC, Boussin F, Herbelin A, De Groote D, Dormont D, Bach JF, Descamps-Latscha B, Zavala F. Eur J Immunol. 1994 Sep;24(9):2055-60. 74. The effect of UVB irradiation on proliferative activity and cell growth potential of cord blood. Greenfeld JI, Noizat-Pirenne F, Hardy MA, Oluwole SF, Hesdorffer CA, Preti RA, De Groote D, Franchimont P. Transplantation. 1994 Aug 27;58(4):504-10. 75. Soluble CD23 potentiates interleukin-1-induced secretion of interleukin-6 and interleukin-1 receptor antagonist by human monocytes. Herbelin A, Elhadad S, Ouaaz F, de Groote D, Descamps-Latscha B. Eur J Immunol. 1994 Aug;24(8):1869-73. 76. Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia. Marchant A, Bruyns C, Vandenabeele P, Ducarme M, Gérard C, Delvaux A, De Groote D, Abramowicz D, Velu T, Goldman M. Eur J Immunol. 1994 May;24(5):1167-71. 77. Cytokines and organ transplantation. A review. Pirenne J, Pirenne-Noizat F, de Groote D, Vrindts Y, Lopez M, Gathy R, Jacquet N, Meurisse M, Honore P, Franchimont P. Nucl Med Biol. 1994 Apr;21(3):545-55. Review. 78. Interleukin-10 production during septicaemia. Marchant A, Devière J, Byl B, De Groote D, Vincent JL, Goldman M. Lancet. 1994 Mar 19;343(8899):707-8. 79. An ELISA for the measurement of human leukemia inhibitory factor in biological fluids and culture supernatants. De Groote D, Fauchet F, Jadoul M, Dehart I, Raher S, Gevaert Y, Lopez M, Gathy R, Franssen JD, Radoux D, et al. J Immunol Methods. 1994 Jan 3;167(1-2):253-61. 80. Elevation of soluble CD23 in serum from patients with blood eosinophilia. Aldebert D, Prin L, Dessaint JP, De Groote D, Capron A, Capron M. Int Arch Allergy Immunol. 1994;103(3):245-51. 81. Tumor necrosis factor receptor expression in HIV-1-infected CD4+ T cells. Hober D, De Groote D, Vanpouille N, Dehart I, Shen L, Wattré P, Maniez-Montreuil M. Microbiol Immunol. 1994;38(12):1005-8. 82. Soluble CD23 and other receptors (CD4, CD8, CD25, CD71) in serum of patients with chronic lymphocytic leukemia. Beguin Y, Lampertz S, De Groote D, Igot D, Malaise M, Fillet G. Leukemia. 1993 Dec;7(12):2019-25.
83. Alloactivation induced during mixed-lymphocyte reaction provokes release of tumor necrosis factor alpha and interleukin 6 by macrophages and primes them to lipopolysaccharides. Toungouz M, Denys CH, De Groote D, Andrien ME, Dupont EC. Hum Immunol. 1993 Nov;38(3):221-5. 84. Impaired phagocyte responses to lipopolysaccharide in paroxysmal nocturnal hemoglobinuria. Duchow J, Marchant A, Crusiaux A, Husson C, Alonso-Vega C, De Groote D, Neve P, Goldman M. Infect Immun. 1993 Oct;61(10):4280-5. 85. Stabilisation of functional tumor necrosis factor-alpha by its soluble TNF receptors. De Groote D, Grau GE, Dehart I, Franchimont P. Eur Cytokine Netw. 1993 Sep-Oct;4(5):359-62. 86. Novel method for the measurement of cytokine production by a one-stage procedure. De Groote D, Gevaert Y, Lopez M, Gathy R, Fauchet F, Dehart I, Jadoul M, Radoux D, Franchimont P. J Immunol Methods. 1993 Aug 9;163(2):259-67. 87. [Central function of the thymus in the recognition of neuroendocrine functions by T lymphocytes during their development]. Geenen V, Martens H, Cormann-Goffin N, Vandersmissen E, Legros JJ, De Groote D, Defresne MP, Boniver J, Franchimont P. Arch Int Physiol Biochim Biophys. 1993 Jul-Aug;101(4):A19-22. Review. French. 88. Soluble CD23 as an effector of immune dysregulation in chronic uremia and dialysis. Descamps-Latscha B, Herbelin A, Nguyen AT, de Groote D, Chauveau P, Verger C, Jungers P, Zingraff J. Kidney Int. 1993 Apr;43(4):878-84. 89. Generation of monoclonal antibodies against HILDA/LIF and their use in the quantitative assay of the cytokine. Godard A, Fauchet F, Raher S, Jadoul M, Thuillier B, Dehart J, Soulillou JP, Baudrihaye M, Jacques Y, De Groote D. Cytokine. 1993 Jan;5(1):16-23. 90. Immunomodulatory properties of cyclic hexapeptide oxytocin antagonists. Geenen V, Martens H, Robert F, Vrindts-Gevaert Y, De Groote D, Franchimont P. Thymus. 1992 Dec;20(4):217-26. 91. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood: II. Application to rheumatoid arthritis and osteoarthritis. Zangerle PF, De Groote D, Lopez M, Meuleman RJ, Vrindts Y, Fauchet F, Dehart I, Jadoul M, Radoux D, Franchimont P. Cytokine. 1992 Nov;4(6):568-75. 92. Metabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy. Joris J, Cigarini I, Legrand M, Jacquet N, De Groote D, Franchimont P, Lamy M. Br J Anaesth. 1992 Oct;69(4):341-5. PMID: 1419439 [PubMed - indexed for MEDLINE] Related citations 93. The thymic education of developing T cells in self neuroendocrine principles. Geenen V, Robert F, Martens H, De Groote D, Franchimont P. J Endocrinol Invest. 1992 Sep;15(8):621-9. Review. No abstract available. 94. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation. De Groote D, Zangerle PF, Gevaert Y, Fassotte MF, Beguin Y, Noizat-Pirenne F, Pirenne J, Gathy R, Lopez M, Dehart I, et al. Cytokine. 1992 May;4(3):239-48. 95. Cytokine serum level during severe sepsis in human IL-6 as a marker of severity. Damas P, Ledoux D, Nys M, Vrindts Y, De Groote D, Franchimont P, Lamy M. Ann Surg. 1992 Apr;215(4):356-62. 96. Intraoperative cytokines production during orthotopic liver transplantation. Pirenne J, Noizat-Pirenne F, De Groote D, Vrindts Y, Lopez M, Gathy R, Damas P, Meurisse M, Jacquet N, Honoré P, Franchimont P. Transpl Int. 1992;5 Suppl 1:S631-5.
97. Immunochemical characterization of antigenic domains on human IL-2: spatially distinct epitopes are associated with binding to the p55 and p70 subunits of IL-2 receptor. Rebollo A, De Groote D, Baudrihay M, Thèze J, Jankovic DL. Mol Immunol. 1992 Jan;29(1):119-30. 98. Prevention of human TNF-induced cutaneous Shwartzmann reaction and acute mortality in mice treated with anti-human TNF monoclonal antibodies. Grau GE, Vesin C, De Groote D, Delacroix D, Gysler C, Piguet PF, Lambert PH. Clin Exp Immunol. 1991 Jun;84(3):411-4. 99. Colocalization of immunoreactive oxytocin, vasopressin and interleukin-1 in human thymic epithelial neuroendocrine cells. Robert F, Geenen V, Schoenen J, Burgeon E, De Groote D, Defresne MP, Legros JJ, Franchimont P. Brain Behav Immun. 1991 Mar;5(1):102-15. 100. Cytokines and DIC in acute leukaemia. Guarini A, Gugliotta L, Bianchi A, De Groote D, Foa R. Eur J Haematol. 1990 Aug;45(2):121-2. No abstract available. Erratum in: Eur J Haematol 1991 Jan;46(1):64. 101. Immunoradiometric assay of parathyrin with polyclonal and monoclonal region-specific antibodies. Bouillon R, Coopmans W, Degroote DE, Radoux D, Eliard PH. Clin Chem. 1990 Feb;36(2):271-6. 102. Idiotypic regulation of the immune system. Common idiotypic specificities between idiotypes and antibodies raised against anti- idiotypic antibodies in rabbits. Winkler M, Franssen JD, Collignon C, Leo O, Mariamé B, van de Walle P, de Groote D, Urbain J. J Exp Med. 1979 Jul 1;150(1):184-95. Other articles 103. Cytokine measurement in serum and plasma with ELISA: getting around the pitfalls. De Groote D. European Clinical Laboratory 1998. 12-14. 104. The total Cytokine Concept: The influence of soluble receptors in the cytokine measurement. Radoux D. and De Groote D. In Cytokine in Cancer Therapy 1994 (Edited by Bergmann L. and Mitrou P. S.), p. 251. Krager, Basel. 105.
Nouvelles approches pharmacologiques basées sur les interactions neuroendocrino-immunitaires
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