Cphs.chula.ac.th

Kanchana Rungsihirunrat, Ph.D. Present address: College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, THAILAND. Phone: (66) 02-218 8154 E-mail address: kanchana.r@chula.ac.th krungsihirunrat@yahoo.com Education: 2003-2007 Ph.D. in Biomedical Sciences, Thammasat University, Thailand. 1992-1995 MSc. in Zoology. Faculty of Science, Chulalokorn University, Thailand. 1988-1991 BSc. in Biology. Faculty of Science, Silpakorn University, Thailand. Research interest: Drug resistance in malaria parasite Molecular Parasitology Thongdee P, Kuesap J, Rungsihirunrat K, Tippawangkosol P, Mungthin M, Na- eroate synthase (dhps) mutant alleles in Plasmodium vivax isolates from Thailand. Acta Tropica. 128(1):137-143. Rugkua R, Rungsihirunrat K. (2013). Implementation of a larval and pupal source reduction program (LSRP) for sustainability in prevention and control of dengue haemorrhagic fever (DHF) in community of Krabi province, Thailand. Journal of Health Research. Vol. 27 No.4 July-August: 225-232. Issaravanich S, Ruangrungsi N, Palanuvej C, Vipunngeun N and Rungsihirunrat K. (2013). Microscopic, molecular and scopolamine content evaluations of Datula metel L. var. metel and D. metel L. var. fastuosa in Thailand. Research Journal of Pharmaceutical, Biological and Chemical Sciences. Vol 4 (2): 1009-1021. Rungsihirunrat K, Kuesap J, Chaijaroenkul W, Na-Bangchang K. (2013). Distribution and emergence of chloroquine –resistant Plasmodium vivax. Journal of Health Research. Vol. 27 No.1 February: 57-65. Kunsorn P, Ruangrungsi N, Lipipun V, Khanboon, Rungsihirunrat K. (2013). The identities and anti herpes simplex virus activity of Clinacanthus nutans and Clinacanthus siamensis. Asian Pacific Journal of Tropical Biomedicine. 3(4):284-290. Win T, Rungsihirunrat K, Siriwong W. (2012). Association of environmental, socio-economic risk factors and dengue prevention practice related to dengue outbreak in Maela Contemporary camp in Tak province, Thailand. Journal of Health Research. Vol. 26 No. 4 July-August. 221-225. Rungsihirunrat K, Chaijaroenkul W, Siripoon N, Seugorn A, Sodsri Thaithong, Na-Bangchang K. (2012). Comparison of protein patterns between Plasmodium falciparum mutant clone T9/94-M1-1 (b3) induced by pyrimethamine and the original parent clone T9/94. Asian Pacific Journal of Tropical Biomedicine. 2(1): 66-69. Kuesap J, Rungsrihirunrat K, Chaijaroenkul W. (2011). Genetics drug resistant malaria. Journal of Vector Borne Diseases. 8(2): 51-58. Thongdee P, Viyanant V, Kuesap J, Rungsrihirunrat K, Tippawangkosol P, Na- Bangchang K. (2012). Genetic polymorphisms of Plasmodium vivax dihydrofolate reductase (Pvdhdr) and dihydropteroate synthase (Pvdhps) in malaria endemic areas of Thailand. Thai J Pharmacology. 34(1): 27-35. Kuesap J, Rungsrihirunrat K, Thongdee P, Ruanweerayut R, Na-Bangchang K. (2011). Molecular characterization of Plasmodium vivax dihydrofolate reductase (Pvdhfr) in Plasmodium vivax isolates from Thailand.Thai J Pharmacology. 33(2): 19-22. Thongdee P, Kuesap J, Rungsrihirunrat K, Tippawangkosol P. (2011). Distribution and pattern of polymorphisms of Plasmodium vivax dihydrofolate reductase (Pvdhdr) and dihydropteroate synthase (Pvdhps) in malaria endemic areas of Thailand. Thai J Pharmacology. 33(1):9-13. Muhamad P, Rungsihirunrat K, , Chaijaroenkul W, Kuesap J, Ruanweerayut R Tippawangkosol P, Na-Bangchang K. (2011). Association between in vitro Sensitivity of Plasmodium vivax Isolates and Polymorphisms of Dihydrofolate Reductase (Pvdhfr) and Dihydropteroate Synthase (Pvdhps). Thai J Pharmacol. 33(1):39-43. Kuesap J, Rungsrihirunrat K, Thongdee P, Ruanweerayut R, Na-Bangchang K. (2011). Change in mutation patterns of Plasmodium vivax dihydrofolate reductase (Pvdhfr) and dihydropteroate synthase (Pvdhps) in P. vivax isolates from malaria endemic areas of Thailand. Memorias do Instituto Oswaldo Cruz. 106(Suppl. I): 130-133. Roonyamarai W, Rungsihirunrat K, Vipunngeun N, and Ruangrungsi N. (2011). Microscopic and molecular analyses of selected Morinda species in Thailand. Asian Journal of Traditional Medicines. 6(3):118-126. Rungsihirunrat K, Chaijaroenkul W, Siripoon N, Seugorn A, Na-Bangchang. (2011). Genotyping of polymorphic marker (MSP3α and MSP3β) genes of Plasmodium vivax field isolates from malaria endemic of Thailand. Tropical Medicine & International Health. 16(7): 794-801. Chaijaroenkul W, Rungsihirunrat K and Na-Bangchang K. (2011). Metabolomics in Parasitology. Journal of Health Research. 25(1: Jan-March): 25-34. Muhamad P, Ruengweerayut R, Chaijaroenkul W, Rungsihirunrat K, Na- Bangchang K. (2011). Monitoring of clinical efficacy and in vitro sensitivity of Plasmodium vivax to chloroquine in area along Thai Myanmar border during 2009-2010. Malaria Journal. 10: 44. Muhamad P, Chaicharoenkul W, Rungsihirunrat K, Ruengweerayut R, Na- Bangchang K. (2011). Assessment of in vitro sensitivity of Plasmodium vivax fresh isolates. Asian Pacific Journal of Tropical Biomedicine. 1:49-53. Vorachate S, Somrongthong R, Rungsihirunrat K. (2010). Satisfaction of Betel Nut Chalk for Aedes Aegypti larva control project, Chaturaphak Phiman District, Roi Et Province, Thailand. Journal of Health Research. 24: (Supplement 2 January-December 2010) 157-162. Mungthin M, Suwandittakul N, Chaijaroenkul W, Rungsrihirunrat K, Harnyuttanakorn P, Seugorn A, and Na-Bangchang K. (2010). The patterns of mutation and amplification of Plasmodium falciparum pfcrt and pfmdr1 genes in Thailand during the year 1988 to 2003. Parasitology Research. 107 (3): 539-545. Hawkins VN, Suzuki SK, Rungsihirunrat K, Hapuarachchi HC, Maestre A, Na- Bangchang K and Sibley CH. (2009). Assessment of the origins and spread of putative resistance-confering mutations in Plasmodium vivax dihydropteroate synthase. Amarican Journal of Tropical Medicine and Hygiene. 81(2): 348-355. Rungsihirunrat K, Chaijareonkul W, Seugorn A, Na-Bangchang K and Thaithong S. (2009). Association between chloroquine resistance phenotype and point mutations in pfcrt and pfmdr-1 in Plasmodium falciparum isolates from Thailand. Acta Tropica. 109: 37-40. Rungsihirunrat K, Sibley CH, Mungthin M, and Na-Bangchang K. (2008). Geographical distribution of amino acid mutations in Plasmodium vivax DHFR and DHPS from malaria endemic areas of Thailand. Amarican Journal of Tropical Medicine and Hygiene. 78(3):462-467. Hawkins VN, Auliff A, Prajapati S, Rungsihirunrat K, Hapuarachchi C, Maestre A, O’Neil MT, Cheng Q, Joshi H, Na-Bangchang K and Sibley CH. (2008). Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase. Malaria Journal. 7:72. Hawkins VN, Joshi H, Rungsihirunrat K, Na-bangchang K and Sibley CH. (2007). Antifolates can have a role in the treatment of Plasmodium vivax. Trends in Parasitology. 23(5): 213-222. Rungsihirunrat K, Na-Bangchang K, Hawkins VN, Mungthin M and Sibley CH. (2007). Sensitivity to antifolates and genetic analysis of Plasmodium viviax isolates from Thailand. Amarican Journal of Tropical Medicine and Hygiene. 76(6): 1057-1065. Seugorn A, Siripoon N, Kanchanakarn N, Rungsihirunrat K, Pumpaibool T, Vichaikatka S, Thaithong S, Harnyuttanakorn P. (2007). Drug Susceptibility of Plasmodium falciparum Collected from Different Areas of Thailand during 2000 – 2001. Journal of Health Research. 21(2):119-24. Rungsihirunrat K, Siripoon N, Pumpaiboon T, Seugorn A and Thaithong S. (2003). Sequence variations of the Plasmodium vivax Dihydrofolate Reductase Gene from Thai isolates. The Journal of Tropical Medicine and Parasitology. 26:1-8. Lopes D, Rungsihirunrat K, Nogueira F, Seugorn A, Gil J, Do Rosario VE and Cravo P. (2002). Molecular characterization of drug resistant Plasmodium falciparum from Thailand. Malaria Journal. 14;1(1):12. Thaithong S, Ranford-Cartwright CL, Siripoon N, Harnyuttanakorn P, Seesod KN, Seugorn A, Rungsihirunrat K, Cravo VL and Beale GH. (2001). Plasmodium falciparum: Gene mutations and amplification of dihydrofolate reductase gene in parasites grown in vitro in presence of pyrimethamine. Experimental Parasitology. 98: 59-70. Others: Kunsorn P, Ruangrungsi N, Lipipun V, Khanboon, Rungsihirunrat K. (2012). Anti herpes simplex virus activity of Clinacanthus nutans and Clinacanthus siamensis. The 4th International Conference on Public Health among Greater Mekong Sub-regional Countries. 15-16 September 2012. Kunming, China. Rungsihirunrat K. (2010). Comparison of protein patterns between Plasmodium falciparum mutant clone T9/94-M1-1(b3) induced by pyrimethamine and the original parent clone T9/94. Proceeding of The XIIth International Congress of Parasitology (ICOPA). August 15-20, 2010. Melbourne, Australia. Issaravanich S, Rungsihirunrat K, and Ruangrungsi N. (2010). Nucleotide sequence of the internal transcribed spacer (ITS) region of Datura metel L. var. fastuosa in Thailand. Proceedings of the 9th Joint Seminar Natural Medicine Research for the Next Decade: New Challenges and Future Collaboration. Bangkok, Thailand. pp. 305-306. Kunsorn P, Ruangrungsi N, and Rungsihirunrat K. (2010). Comparison of ITS sequence between Clinacanthus siamensis and Clinacanthus nutans. Proceedings of the 9th Joint Seminar Natural Medicine Research for the Next Decade: New Challenges and Future Collaboration. Bangkok, Thailand. pp. 307-308. Rungsihirunrat K. (2010). Genotyping of polymorphic marker gene: PvMSP3α and PvMSP3β genes of Plasmodium vivax field isolates from malaria endemic areas of Thailand. Proceeding of 32nd Pharmacological and Therapeutic Society of Thailand Meeting. Thai Journal of Pharmacology. Vol. 32 No. 1, 2010. p. 317. ISSN 0125-3832. Rungsihirunrat K, Sibley CH, Mungthin M, and Na-Bangchang K. (2008). Geographical distribution of amino acid mutations in Plasmodium vivax DHFR AND DHPS from malaria endemic areas of Thailand. Proceeding of The XVIIth International Congress for Tropical Medicine and Malaria (ICTM2008). September 29-October 3, 2008. International Convention Center Jeju, Jeju, Korea. Rungsihirunrat K. (2007). Sensitivity to antifolates and genetic analysis of Plasmodium viviax isolates from Thailand. Proceeding of The RGJ-Ph.D. Congress VIII, Oct 19-21, 2007 at Jomthien Palm Beach and Resort, Pattaya, Chonburi, Thailand. Rungsihirunrat K, Na-Bangchang K and Sibley CH. (2006). Can antifolates have a role in vivax chemotherapy? Proceeding of The Seattle Parasitology Conference, May 18-19, Seattle Biomedical Reseach Institute (SBRI), 307 Westlake Ave, Suite 500, Seattle, WA 98109. Lopes D, Rungsihirunrat K, Nogueira F, Seugorn A, Gil J, Do Rosario VE and Cravo P. (2002). Molecular markers of Plasmodium falciparum drug resistance in Thailand: complete selection of pfcrt76 by chlroquine. Proceeding of the 3 European Congress on Tropical Medicine and International Health. Lisbon, Portugal.

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