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James Bard, Senior Inspector: Mr. Bard has 12 years of
experience in roadway construction. Mr. Bard is CTQP Florida Department of Transportation – District VI Certified and has experience in the following areas: Ms. Carol Cann, Professional Services Unit Letter of Response (Contract 13609)
• Experience with the installation and relocation of CIMA is pleased to submit this Letter of Response to
provide Construction Engineering and Inspection (CEI) services for the upcoming I-395 widening project in Miami Johnnie Powell, Senior Inspector: Mr. Powell has 26
Dade County for the Florida Department of years of experience in roadway and bridge construction.
Transportation (FDOT). CIMA’s Main Office will be in
Mr. Powell is CTQP Certified and has experience in the CIMA a Certified DBE firm with the Florida Department of
Transportation is also prequalified with the department in AVAILABILITY OF STAFFING:
CIMA’s proposed staffing is available as per organization
• Counseled and trained in better living approaches to handle management and dialogue on project RELEVANT EXPERIENCE OF STAFFING:
Eddie Rodriguez, Inspector: Mr. Rodriguez has 8 years
Vladamir Melguizovski, E.I., Project Engineer: Mr.
of experience in roadway and utilities construction. Mr. Rodriguez is CTQP Certified and has experience in the Melguizovski a graduate Civil Engineer has 12 years of experience in the construction and management of heavy Civil Projects to include to roadway and bridges. Mr. Melguizovski has experience in the following areas: • Experience as a Public Information Officer on • FDOT Construction Management Procedures • FDOT Material Specifications Packages Jose A. Gonzalez, P.E. Quality Assurance: Mr.
Gonzalez a Professional Engineer with over 22 years of • Management of Roadway and Bridge Contractors experience in the Construction Engineering and Inspection services will be performing Quality Assurance reviews. CIMA will be implementing a complete project QA review • Fluent in Spanish, English and French in order to improve our procedures and services to the • Awaiting Results from April 2012 PE Test department along with insuring success to this project. Construction Engineering and Inspection Services for I -395 Widening Page 1 of 2 project issue quickly to avoid delays. Aside from RELEVANT PROJECT ISSUES: CIMA has reviewed
discussing project specific information all interested project site and will assist the department to eliminate parties are welcome to view any concerns during the construction which might affect their organization and a solution will be discussed during the meeting or at least the commencement of the solutions to avoid delays and IMPACT ITEMS TO PROJECT
CIMA will insure that all activities and lanes closures are Weekly Progress Meetings: In the weekly progress
co-ordinated with adjacent FDOT Port of Miami Tunnel meetings, CIMA will discuss with contractors a look Project to the east and MDX’s 836 pavement ahead schedule for the subsequent week construction rehabilitation project to the west of project location. This will reduce time extensions due to adjacent projects. activities and review the status of such activities the following week. Contractor’s are asked and documented, CIMA will co-ordinate with the Miami Parking Authority all work to be performed over their facilities located if any delays or extra work for the previous week were under the bridges and side street widening. This will encountered. This is done to track construction activities reduce time delays due to constructability issues. and determine any delays that might be occurring in CIMA will co-ordinate Ramp Closure with the FDOT PIO order to mitigate additional time and cost to complete and local community ahead of time insure that no delays project within the set goals. This will also allow Mr. are experienced during construction. Project has several Melguizovski to eliminate encountered delays by key community venues such as the American Airlines providing solutions on future construction activities. Also Arena and Miami Performing Art Center, both have the weekly progress meeting which coincides with events thru out the entire year and key co-ordination is FDOT’s cutoff date for payment will be a monthly required to avoid delays in construction. progress meeting which the contractor is to submit all CIMA will insure that key activities such as pile driving pertinent documents for payment to include an updated and demolition occur during daytime hours to avoid night project schedule and a monthly progress report. time complaints and if night time work is inevitable then Submittals and RFI: A submittal log will be used in
coordinate work hour limits till midnight. This will reduce order to track all shop drawings and submittals. This log will forecast due dates for submittals and track them in CIMA will insure that before all lane and ramp closures order to avoid any delays which are 28days for the first are implemented that the contractor has had a prework submittal and 14 days for a re-submittal. CIMA will meeting to include subs and materials. Our goal is to review the submittal log on a weekly basis in order to reduce closures on the project and insure contractor is RFI's and forward for disposition to the appropriate organization. All RFI's will be answered by the CIMA APPROACH TO ADMINISTRATION:
Project Team within 10 days. RFI's are time critical significant experience in FDOT construction management. items, which deserve prompt and accurate resolutions in The following are key items that will insure timely order to avoid delays and claims. RFI’s will be logged and tracked on a weekly basis in the progress meetings. KEY ADMINISTRATION ITEMS
CIMA is looking forward in collaborating with the
department and insuring the success of the I-395 widening
Preconstruction Conference: Initial Communications
are established upon receipt of our Notice to Proceed with all parties having an interest in the project. This will include FDOT Personnel, Local and State Agencies, Law Enforcement Agencies, and Utility Companies. The participation of these individuals and entities is important to a successful project. They will all be invited to the Pre-construction Conference where Mr. Melguizovski will familiarize them with the Team’s approach to this project. This meeting will also develop lines of communications and contact information to resolve any Construction Engineering and Inspection Services for I -395 Widening Page 2 of 2 Construction Engineering and Inspection Services for I -395 Widening Page 1 of 1 VLADIMIR MELGUIZOVSKI, E.I.
PROJECT ENGINEER
(12 YEARS OF EXPERIENCE)


DEGREES AND AFFILIATIONS:
Bachelor of Science in Civil Engineering, Javeriana University
Master of Science in Construction Management, Javeriana University
LICENSES AND CERTIFICATIONS:
Licensed Engineer Intern, State of Florida No. 1100008838
CTQP Tin No. M422298594700, Asphalt Paving Level I & II, Earthwork Level I & II, Concrete Level 1, Drill Shaft, Pile Driving,
QC Manager, Final Estimates Level 1
OTHER TRAINING:
ACI Concrete, FDOT MOT, Radiation Safety
EXPERIENCE:
NOVEMBER 2011 TO MARCH 2012
Project Engineer for the reconstruction of Route 1285 (Flowing Well Rd) $314,400.30 at the Seminole Tribe Of
Florida Brighton: Richard Pereira (954) 985-2300
JUNE 2011 TO SEPTEMBER 2011
Senior Inspector on the $635,000.00 Water Main project in the North Shore area of Miami Beach from 85 Street to 73 Street
Along Byron Ave, Tatum Waterway and Dickens Road. This watermain was constructed with a residential community and
involved Roadway restorations.
FEBRUARY 2010 TO MARCH 2011
Project Engineer/Sr. Inspector for Seminole Tribe of Florida Snake Road and Bridge Project Reconstruction of BIA
Route 1281 bridge approaches and utilities, a $2.3 million reconstruction project. Director of Transportation: Richard
Pereira (954) 985-2300
NOVEMBER 2009 TO FEBRUARY 2010
Construction Inspector for City of Fort Lauderdale, Fire Stations #29, #49, and #3. Responsible for daily documentation of
construction activities, materials testing, foundations structures and site work.
APRIL 2009 TO OCTOBER 2009
Construction Inspector for US-1 Project in Vero Beach, FL. for FDOT District IV which includes milling and resurfacing,
widening, lighting and signalization improvements. FDOT Project Administrator: Kristopher Kehres (772)618-3761
JANUARY 2006 TO OCTOBER 2007
Assistant Project Manager / Cost Engineer providing support to the Senior Project Manager in managing and controlling
various projects on $2.7 Billion North Terminal Development Program at Miami International Airport. Managed construction
changes including reviewing contractor proposals, prepared change/work orders, coordinated negotiation meetings and
construction meetings, reviewed pay applications and schedule of values.
MARCH 2005 TO DECEMBER 2005
Senior Roadway / Bridge Inspector on the SR-9 (Interstate I-95) reconstruction from 12th Avenue South to 10th Avenue
North in Palm Beach County, FL. Responsible for implementation of the Contractor’s quality control plan for all asphalt,
concrete and earthwork construction on the project in conformance with section 105 of the FDOT specifications. JANUARY
2003 TO FEBRUARY 2005
Roadway Inspector for the Miami-Dade Department of Environmental Resource Management (DERM) Drainage Cleanup
Program. Supervised several Contractors performing pipe desalting and storm sewer system clean up operations all
throughout Miami Dade County. Documented all work accomplished daily to verify contractors invoices, ensured all drainage
systems were effectively functioning after task completion and assisted Senior Inspector in other duties.
JUNE 2001 TO DECEMBER 2002
Senior Inspector on I-95 sound wall project from SR 112 to Broward County Line. This project also included Concrete
Pavement Construction.
JANUARY 2001 TO MAY 2001
Project Field Engineer responsible for Construction Management functions for the $82 million Fort Lauderdale-
Hollywood International Airport Interchange Task 2 design-build project. Specific
responsibilities included quality control, compliance with contract documents, progress schedules, field engineering
records, quantity take off, shop drawings, as-built drawings and assisting Senior Site Superintendent.
JUNE 2000 TO DECEMBER 2000
Project Field Engineer responsible for construction site functions for the $20 million Suncoast Parkway Section 1 located in
Lutz, Florida. This project was a fast track completion project and included completion of 4.1 miles of interstate construction
including five bridges and various roadway features.
JAMES BARD
SR. INSPECTOR
(12 YEARS OF EXPERIENCE)


DEGREES AND AFFILIATIONS:
School Diploma, Florida Junior College, 1980
CTQP CERTIFICATIONS: Tin No. B630450614520
Asphalt Paving Level I & II, Quality Control Manager, Earthwork Inspector Level I & II, Final Estimates Level I & II,
FDOT Concrete Field Technician Level I, Drill Shaft.
OTHER TRAINING:
Troxler Nuclear Safety, ACI Level I, IMSA Traffic Signals Level I, OSHA Certified, Florida FDEP SWPPP Certified,
National Cable Training Institute, 1996, Certified Commscope 2000, Certified Society of Cable Technology Engineers
1997, Cricket Wireless, (Site Acquisition) 2000 & 2001, Electronics & Test Equipment; Calan Electronics, 1998, Fiber
Optics; Pirelli Fiber, 1998 , FDOT Intermediate MOT
EXPERIENCE:
MARCH 2012 TO AUGUST 2012
Senior Inspector on Construction Engineering and Inspection Services Fin: 406150-5/7-52-01 Turnpike - Milling and
resurfacing from Atlantic Blvd. to Palm Beach County Line. FDOT Project Manager Pacifico Castillo, P.E. (954) 934-
1118
JANUARY 2011 TO MARCH 2012
Senior Inspector on Construction Engineering and Inspection Services MDX Project #40027 to perform project
oversight and inspection on Guardrail Installation on SR 836: Assistant Director of Engineering, Juan Toledo P.E.
(305)637-3277
FEBRUARY 2008 TO OCTOBER 2010
Project Administrator for Fin: 213272-4-52-01 SR 8 (I-10) expansion overseeing multiple contractors in the widening
and reconstruction project. This project consists of rebuilding and expanding 8 miles of Interstate 10 from a 4 lane
roadway to a 6 lane roadway including the reconstruction of Chaffee Road and Cahoon Road bridges. Chaffee Bridge
reconstruction utilizing U- beams, Cahoon Road overpass bridge widening, drainage system installation, jack and
bore drainage, sidewalk and curb ramps, installation of approximately 1, 000 linear feet of a 16 Water Main and 2,
300 linear feet of a 8 Force Main including HDPE directional drills, new highway lighting system, signalization, sign
structures and pavement markings. Shannon Mobley/FDOT project manager (386) 758-3714
MARCH 2008 TO OCTOBER 2010
Senior Project Inspector for Wiles Road construction project. Duties included inspection on drainage structures, water
mains, hydrants, services ,canal dredging, pile driving, electrical / interconnect cable installation, and signalization
and embankment construction for a new Bridge over Florida Turnpike Enterprise and new roadway construction to tie
Powerline Road to Lyons Road. Jorge Ortiz Broward County Project Engineer (954) 577-4583
SEPTEMBER 2006 TO FEBRUARY 2008
Contract Support Specialist for the Sawgrass Widening Project (Coral Ridge Drive to Atlantic Blvd), Broward County,
Florida Fin: 420289-6-52-01. In charge of LIMS Data input and tracking for all 5 projects and projects solve shop
drawing and RFI's. Inspected and tested fiber optics and cameras for a 30- mile stretch along the Sawgrass
Expressway and monitored Vehicle Detection Systems, pole installations, and splice vaults, pulls boxes, and required
hook- ups. Also tested and verified CCTV, DMS, and VDS equipment and street lighting for Turnpike Enterprises
contact person Mario Rojas (954) 975-4855
JANUARY 2004 TO AUGUST 2006
Construction Engineering Inspector for Olive Ave (SR-5) project in downtown West Palm Beach. Responsible for
measuring and tracking all pay-items and daily’s for data entry on monthly pay estimates, explaining P.R. work
between local business and City, County, State FDOT about construction activities affecting local traffic, business and
utilities shut-off’s, and inspection of maintenance of traffic. Additional responsibilities included materials inspections
for asphalt, concrete, earthwork and concrete, overseeing of multiple contractors from the prime to subcontractors
accounting for time, materials, labor and equipment for payment. Contact: Jeff Daugherty (561) 659-3680
JULY 2003 TO DECEMBER 2003
BELLSOUTH Field Engineer responsible for overseeing Bellsouth's fiber and cable lines, identifying and relocating
them for new construction, and keeping communications safe from damage. Contact: Gabriel Rivera (954) 868-9725
MARCH 2000 TO FEBRUARY 2002
ACCELERA/MIDWEST WIRELESS Field Engineer in the wireless communication field overseeing
multiple contractors from search rings to closings. Performed bid-walks, ordering BOM’s, and overseeing
construction of sites both raw land and co-locates followed by closings, while managing my department of
site acquisition and zoning lawyers and maintaining progress meetings to finish our projects ahead of
schedule. Contact Jim Hatmaker VP Mid West Wireless
Resume of James Bard
JOHNNIE M. POWELL, JR
SR. INSPECTOR
(26 YEARS OF EXPERIENCE)


DEGREES AND AFFILIATIONS:
Construction Management, University of South Florida, 1986Associate of Science, Computer Engineering
Technology, National Education Center, Tampa Institute Campus, 1985
McArthur High School, 1981

CTQP CERTIFICATIONS:
Tin No. 400433632430400433632430
Asphalt Paving Technician Level I, Earthwork Construction Inspection Level I, Earthwork Construction Inspection
Level II, Concrete Field Technician – Level I, Drilled Shaft Inspector, Asphalt Paving Technician Level II
OTHER TRAINING:
ACI - Concrete Field Testing Technician - Grade I, TROXLER - Nuclear Density Gauge Operator, FDOT - Pile
Driving Installation Inspection, ATTSA – Florida Intermediate Work Zone Traffic Control
EXPERIENCE:
JANUARY 2011 TO MARCH 2012
Atlantic Boulevard at Rock Island Road Intersection Improvements, Construction Engineering Inspection (CEI) –
Broward County, Florida Project length: 0.5 miles. Roadway Inspector in charge of the construction inspection of a
WB left turn lane, WB right turn lane, and dual left-turn lanes on all four legs of the intersection. . Mr. Richard
Tornese, PE, (954) 577-4579
JANUARY 2011 TO MARCH 2012
Hillsboro Boulevard at Military Trail Intersection Improvements, Construction Engineering Inspection (CEI) – Broward
County, Florida Project length: 0.8 miles. Roadway Inspector project consists of widening Military Trail with the
addition of northbound and southbound through lanes. Mr. Richard Tornese, PE, (954) 577-4579
2009
SR-AIA – Vero Beach, Florida Superintendent – He was responsible for median landscape improvement projects.
Reference: Mr. Gary Basham, Project Engineer/Project Manager
2004 - 2007
Julia Tutle Causeway SR-112, University Drive from SR-84 to Broward Boulevard and south bound I-95 off campus at
Griffin Road- Senior Bridge/Roadway Inspector responsible for all repairs to steel and concrete beams, metalizing
and cathodic protection to beams, columns, caps and struts.Mr. Rudy Batz, Project Manager – FDOT, District 6
2001- - 2004
Quality Neighborhood Improvement Program (QNIP) DERM and Miami-Dade County Public Works Projects
Roadway/Bridge Inspector –. Mr. Joaquin Rabasa, PE, Project Manager
2001
Roadway Inspector – performed all the required roadway inspections including, but not limited to, embankment,
subgrade, optional base courses, curb and gutter, drainage, utility relocations, guardrail installations, signalization.
1998 - 2001
Bridge Inspector –responsible for different phases of inspection, from drilled shaft operations, footers, columns, pet-
bearings, grouting operations, grinding and grooving bridge deck. Mr. Greg Lady, Project Manager – FDOT, District 4
1997 - 1998
Bridge Inspector – responsible for bridge repairs, approach slabs and drainage installation, (MOT) reports, a density
logbook and daily reports of contractor’s and subcontractor’s duties.
1994 - 1997
Density Inspector – responsible for all Compaction Control for I-95. This was a widening project in Miami, Florida,
under the Authority of the FDOT, District 6. Ms. Anna Bernal and Mr. Stu Smith, Project Manager – FDOT, District 6
1992 - 1994
Bridge Inspector – He was responsible for the inspection of steel, concrete and post-tensioning operations. Mr. Tony
Grau, Project Manager – FDOT, District 6
1988 - 1992
Bridge/Roadway Inspector – He handled project inspection of form work for footer, columns, cap and beam
placements, steel and concrete placements for bridge decks. He performed density test on limerock base material
and daily documentation of inspector reports.
1986 - 1987
Florida Department of Transportation (FDOT) West Palm Beach Construction, Palm Beach County Roadway
Inspector
EDUARDO R. RODRIGUEZ
INSPECTOR
(8 YEARS OF EXPERIENCE)



DEGREES:
Bachelor of Science in Communication, Florida International University, 1998
LICENSES AND CERTIFICATIONS:
Concrete Specifications 346,347, and 400
CTQP Asphalt Paving Level I, CTQP Earthwork Construction Inspection Level
OTHER TRAINING:
TROXLER – Radiation Safety, ACI Level I, FDOT MOT Intermediate, IMSA Certified Inspector
EXPERIENCE:
2011 TO 2012
Nautilus Neighborhood No. 7 Improvements (Miami Beach, Fl) 27+m project, for the City of Miami Beach Capital
Improvements Program in Miami-Dade County. Assisted in resident’s notifications and public’s assistance arising
from project’s impact and progression. Coordinated and inspected all roadway construction activities for GC &
subcontractors, including but not limited to inspections of earthwork, potable water main installation, drainage
improvements, pump stations & pressure wells installation. Worked extensively with landscape coordination for entire
project. (i.e: as-builds coordination, resident’s change-requests, quality control, among others)

2010 TO 2011
Washington Avenue Improvements Program (Miami Beach, Fl) Washington Avenue, from 5th Street to Lincoln Road,
13+ m project for the City of Miami Beach-CIP Office. Coordinated with the City of Miami Beach’s Project CEI, Hazen
and Sawyer, inspection staff, public sector, subcontractors as well as the City’s PWD for completion of design work.
Responsible for overseeing contractor personnel’s work in the potable water main system installation, drainage
improvements, gravity well drilling and capacity inspection, hardscape work lighting, signalization, asphalt paving,
entire landscaping work and all of project’s as-built information gathering and sketching.

2004 TO 2011
Lummus Neighborhood Improvements (Miami Beach, Fl Flamingo / Lummus, 13+m project, for the City of Miami Beach CIP
Office in Miami-Dade County. Assisted in resident’s notifications and public’s assistance arising from project’s impact and
progression. Inspected all roadway construction activities including but not limited to inspections of earthwork, potable water
main installation, drainage improvements, milling/resurfacing/asphalt paving, lighting, signalization, concrete work (curb &
gutter, sidewalk-exist/new land survey implementation) and maintenance of traffic inspections throughout 6th street to
Española way.
JOSE A. GONZALEZ, P.E.
PRESIDENT / QUALITY ASSURANCE
(25 YEARS OF EXPERIENCE)


DEGREES:
Bachelor of Science in Civil Engineering, Florida International University, 1989
LICENSES:
Certified Professional Engineer in Florida License No. 47519
Certified General Contractor in Florida License No. CGC 1505020
Certified Under Ground Contractor in Florida License No. CUC 1223853
Miami Dade County Structural Engineer Contractor
CTQP CERTIFICATIONS:
Tin#: G524421644410. Asphalt Roadway I & II, Asphalt Plant II, Earthwork I & II, QC Manager, Drill Shaft, Final Estimates I & II

OTHER TRAINING:
ATTSA: MOT Advanced, Radiation Safety Officer, FDOT: Final Estimates, Claims Review, Site Manager, LIMS, TSO, IMS
EXPERIENCE:
NOVEMBER 2011 TO MARCH 2012
Project Engineer for the reconstruction of Route 1285 (Flowing Well Rd) $314,400.30 at the Seminole Tribe Of Florida
Brighton Reservation. Director of Transportation: Richard Pereira (954) 985-2300
FEBRUARY 2010 TO MARCH 2011
Senior Project Engineer for Seminole Tribe of Florida’s $2.3 million Snake Road and Bridge Project. Director of
Transportation Richard Pereira (954) 985-2300
JUNE 2009 TO JUNE 2010
Senior Project Engineer on the $4.9 million Perimeter Road reconstruction project from NW 72nd Ave to NW 57th Ave.:
Client: FDOT D6 Project Manager: Victor Ortiz (305) 525-4956
JANUARY 2009 TO AUGUST 2010
Construction Manager for City of Fort Lauderdale, Fire Stations 29, 49, and 3. Project Manager: Mark Friedman, AIA
(954) 828-5952.
DECEMBER 2007 TO DECEMBER 2008
Senior Project Engineer for the $4.2 million SR-823/Red Road (2.0 Miles) and $2.5 million SR-823/Flamingo Road (1.3
Miles). FDOT D4 Project Manager: Rudi Batz (954) 958-7642
JANUARY 2006 TO MARCH 2007
Senior Project Engineer SR 862 (I-595) Pine Island to Davie Rd. (2.7 Miles) $4.9 mil. SR 9 I-95 SB Ramp at Hollywood
Blvd. (.4 Miles) $1.4 mil. SR 9 I-95 SB Ramp at Griffin Road (.3 Miles) $1.3 mil. Client: FDOT D4 Project Manager: Rudi
Batz (954) 958-7642
JUNE 2004 TO JANUARY 2006
Senior Project Engineer SR 817 University Drive from SR 84 to SR 842 (1.4 Miles) $6.4 mil Client: FDOT D4 Project Manager:
Rudi Batz (954) 958-7642
MARCH 2003 TO JUNE 2004
Project Engineer for Fly-over West Bound State Road 836 to Florida Turnpike (2 Miles) $36 mil. Client: MDX Authority
Project Manager: Valentine Onuigbo (305) 637-3277
NOVEMBER 2002 TO MARCH 2003
Multiple Civil projects performing CQC, Design and Construction.
DECEMBER 2001 TO NOVEMBER 2002
Senior Project Engineer SR 932 Coral Way between 37 Ave and 12 Ave (4 Miles) $5.5 mil Client: FDOT D6 Project
Manager: Saud Khan (305) 499-2370
JULY 2000 TO DECEMBER 2001
Founded CIMA Engineering Corp. and worked on various Civil projects performing project management.
JULY 1999 TO JULY 2000
FDOT - Senior Project Engineer for several District VI construction projects, Project Manager: Ali Al-Said (305) 499-2370
MARCH 1999 TO JULY 1999
Dade Transportation Consultants - GEC for Miami Dade Expressway Authority responsible for development of construction
program along with development of design-build RFP’s. Director of Engineering: Samuel Gonzalez (305) 637-3277
AUGUST 1994 TO MARCH 1999
Senior Project Engineer for several FDOT District IV construction projects. TREN URBANO - Resident Engineer for Phase 1 of a
$150 million light rail project in San Juan, Puerto Rico. FDOT - Project Engineer for a $7.7 million reconstruction of the six lane
Bird Road roadway (appx, 3.0 miles)

Source: ftp://ftp.dot.state.fl.us/LTS/D6/Professional%20Services/Fiscal%20Year%202012-2013/13609%20-%20251688-3-62-01/Longlist%20&%20Shortlist%20Selections/Letters%20of%20Response/CIMA.pdf

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Walter G. Zumft Nitrate and nitric oxide, in addition to being respiratory substrates, are signal molecules for the induction of N-oxide-metabolizing enzymes. The NO signal is processed by transcription factors of the Crp-Fnr superfamily. Denitrification is intimately related to other cellular processes such as primary and secondary transport, protein translocation, cytochrome c biogen

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Adopted from the “NOTE FOR GUIDANCE ON THE INVESTIGATION OF BIOAVAILABILITY AND BIOEQUIVALENCE”(The European Agency for the Evaluation of Medicinal Products, London, 26 July 2001, CPMP/EWP/QWP /1401/98 ) with some adaptation for ASEAN application. 2.2 Pharmaceutical alternatives 2.3 Bioavailability 2.4 Bioequivalence 2.5 Essentially similar products 2.6 Therapeutic equivalence 3. DESI

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