About Heart Failure
The term "heart failure" makes it sound like the heart is no longer working at all and there's nothing that
can be done. Actually, heart failure means that the heart isn't pumping as well as it should be.
Your body depends on the heart's pumping action to deliver oxygen- and nutrient-rich blood to the body's
cells. When the cells are nourished properly, the body can function normally.
With heart failure, the weakened heart can't supply the cells with enough blood. This results in fatigue and
shortness of breath. Everyday activities such as walking, climbing stairs or carrying groceries can become
Heart failure is a serious condition, and usually there's no cure. But many people with heart failure lead a
full, enjoyable life when the condition is managed with heart failure medications and healthy lifestyle
changes. It's also helpful to have the support of family and friends who understand your condition.
How the normal heart works
The normal healthy heart is a strong, muscular pump a little larger than a fist. It pumps blood continuously
The heart has four chambers, two on the right and two on the left:
Two upper chambers called atria (one is an atrium)
Oxygen-rich blood travels from the lungs to the left atrium, then on to the left ventricle, which pumps it to
The right atria takes in oxygen-depleted blood from the rest of the body and sends it back out to the lungs
The heart pumps blood to the lungs and to all the body's tissues by a sequence of highly organized
contractions of the four chambers. For the heart to function properly, the four chambers must beat in an
What is heart failure?
Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough
blood through to meet the body's needs for blood and oxygen. Basically, the heart can't keep up with its
At first the heart tries to make up for this by:
Enlarging. When the heart chamber enlarges, it stretches more and can contract more strongly,
Developing more muscle mass. The increase in muscle mass occurs because the contracting
cells of the heart get bigger. This lets the heart pump more strongly, at least initially.
Pumping faster. This helps to increase the heart's output.
The body also tries to compensate in other ways:
The blood vessels narrow to keep blood pressure up, trying to make up for the heart's loss of
The body diverts blood away from less important tissues and organs to maintain flow to the most
These temporary measures mask the problem of heart failure, but they don't solve it. Heart failure
continues and worsens until these substitute processes no longer work.
Eventually the heart and body just can't keep up, and the person experiences the fatigue, breathing
problems or other symptoms that usually prompt a trip to the doctor.
The body's compensation mechanisms help explain why some people may not become aware of their
condition until years after their heart begins its decline. (It's also a good reason to have a regular checkup
Heart failure can involve the heart's left side, right side or both sides. However, it usually affects the left
Types of Heart Failure
The heart's pumping action moves oxygen-rich blood as it travels from the lungs to the left atrium, then on
to the left ventricle, which pumps it to the rest of the body. The left ventricle supplies most of the heart's
pumping power, so it's larger than the other chambers and essential for normal function. In left-sided or
left ventricular (LV) heart failure, the left side of the heart must work harder to pump the same amount of
There are two types of left-sided heart failure. Drug treatments are different for the two types.
Systolic failure: The left ventricle loses its ability to contract normally. The heart can't pump with
enough force to push enough blood into circulation.
Diastolic failure (also called diastolic dysfunction):
The left ventricle loses its ability to relax
normally (because the muscle has become stiff). The heart can't properly fill with blood during
The heart's pumping action moves "used" blood that returns to the heart through the veins through the
right atrium into the right ventricle. The right ventricle then pumps the blood back out of the heart into the
Right-sided or right ventricular (RV) heart failure usually occurs as a result of left-sided failure. When the
left ventricle fails, increased fluid pressure is, in effect, transferred back through the lungs, ultimately
damaging the heart's right side. When the right side loses pumping power, blood backs up in the body's
veins. This usually causes swelling in the legs and ankles.
Congestive heart failure is a type of heart failure which requires seeking timely medical attention,
although sometimes the two terms are used interchangeably.
As blood flow out of the heart slows, blood returning to the heart through the veins backs up, causing
congestion in the body's tissues. Often swelling (edema) results. Most often there's swelling in the legs
and ankles, but it can happen in other parts of the body, too.
Sometimes fluid collects in the lungs and interferes with breathing, causing shortness of breath,
especially when a person is lying down. This is called pulmonary edema and if left untreated can cause
Heart failure also affects the kidneys' ability to dispose of sodium and water. This retained water also
increases swelling in the body's tissues (edema).
Classes of Heart Failure
Doctors usually classify patients' heart failure according to the severity of their symptoms. The table
below describes the most commonly used classification system, the New York Heart Association (NYHA)
Functional Classification. It places patients in one of four categories based on how much they are limited
Functional Capacity: How a patient with cardiac disease feels during
Class physical activity
Patients with cardiac disease but resulting in no limitation of physical
activity. Ordinary physical activity does not cause undue fatigue,
palpitation, shortness of breath or chest pain.
Patients with cardiac disease resulting in slight limitation of physical
activity. They are comfortable at rest. Ordinary physical activity results in
fatigue, palpitation, shortness of breath or chest pain.
Patients with cardiac disease resulting in marked limitation of physical
activity. They are comfortable at rest. Less than ordinary activity causes
fatigue, palpitation, shortness of breath or chest pain.
Patients with cardiac disease resulting in inability to carry on any physical
activity without discomfort. Symptoms of heart failure or the chest
syndrome may be present even at rest. If any physical activity is
Class Objective Assessment
No objective evidence of cardiovascular disease. No symptoms and no
limitation in ordinary physical activity.
Objective evidence of minimal cardiovascular disease. Mild symptoms and
slight limitation during ordinary activity. Comfortable at rest.
Objective evidence of moderately severe cardiovascular disease. Marked
limitation in activity due to symptoms, even during less-than-ordinary
Objective evidence of severe cardiovascular disease. Severe limitations.
Experiences symptoms even while at rest.
Warning Signs of Heart Failure
Sign or Symptom
People with Heart Failure
Why It Happens
Shortness of breath (also called dyspnea)
rest, or while sleeping, which (the vessels that
while lying flat and may need heart can't keep up
Buildup of excess fluid in body tissues (edema) .swelling in the feet, ankles, As blood flow out of
gain. You may find that your blood returning to
activities, such as shopping, to meet the needs
of disorientation. A caregiver certain substances
Conditions That May Lead to Heart Failure
If you have heart failure, chances are you have (or had) one or more of the conditions listed below
. Some of these can be present without you knowing it. Typically these
conditions cause the "wear and tear" that leads to heart failure. Having more than one of these factors
Conditions that may lead to heart failure include:
2. Past heart attack (myocardial infarction)
5. Heart muscle disease (dilated cardiomyopathy, hypertrophic cardiomyopathy) or
Treatment of Heart Failure
Taking your medicines as directed may decrease your symptoms, and prevent your heart failure from getting worse. Keep a written list of the medicines you take, the amounts, and when and why you take them. Put your medicines in a pillbox placed in an area you can easily see. Use a timer to help you remember when to take your medicine. Bring a list of your medicines, or the pill bottles, when you see your caregivers. Ask your caregiver for information about your medicine.
use any medicines, over-the-counter drugs, vitamins, herbs, or food supplements without
first talking to caregivers.
stop taking your medicines without talking to your caregiver. Ask your caregiver what to
do if you miss taking a dose of your medicine. Call your caregiver if you think your medicines are
not helping, or if you feel you are having side effects. Use all of your medicines given to control
other health conditions as directed by your caregiver. These conditions include diabetes and high
blood cholesterol. If you are taking medicine that makes you drowsy, do not drive or use heavy
The following heart medicines may be used to treat your heart failure:
o ACE inhibitors:
ACE inhibitors improve the function of your heart. This medicine is given
to decrease your symptoms and slow your heart failure.(Example Altace, Lisinopril, Zestril)
Angiotensin II receptor blockers:
You may need angiotensin II receptor
blockers (ARBs) if you cannot take ACE inhibitors. ARBs help your heart beat stronger to decrease your symptoms. (Examples: Atacand, Avapro, Benicar, Diovan)
o Aldosterone antagonists:
Aldosterone antagonists block the hormone (body chemical)
called aldosterone. The medicine helps remove extra fluid from your body and protect your heart from further damage.(Examples: Inspra, Aldactone)
o Beta blockers:
Beta blockers help your heart pump strong and regular. (Examples:
o Cardiac glycosides:
Cardiac glycoside medicine helps your heart beat strongly and
decreases abnormal heartbeats.(Example: Digoxin)
Nitrates help improve the blood flow through your heart. (Examples: IMDUR,
Vasodilators may improve blood flow by making the blood vessels in your
heart and lungs wider. (Example Hydralazine)
You may need to take an aspirin a day to help prevent heart problems. Aspirin helps to
prevent blood clots from forming and causing blood flow problems in the heart. If caregivers want
you to take aspirin daily, do not
take acetaminophen or ibuprofen instead. Do not take more or
less aspirin than caregivers say to take. If you are on other blood thinner medicine, ask your
caregiver before you take aspirin for any reason.
Diuretics help your body get rid of edema (extra fluid) in your lungs and around your
heart. This medicine will also help get rid of extra fluid in your legs and ankles. You may urinate
more often when taking diuretics.(Examples: Lasix/furosemide, Bumex/bumetanide,
You will need to limit the alcohol you drink, or avoid alcohol completely. Drinking too much alcohol can damage your brain, heart, and liver. Drinking too much alcohol can worsen your heart
failure and increase your blood pressure. Women should limit alcohol to one drink a day. Men should limit alcohol to two drinks a day. A drink of alcohol is 12 ounces of beer, or five ounces of wine. One and one-half ounces of liquor, such as whiskey, is one drink of alcohol.
drink any alcohol if you have had problems with drinking too much alcohol in the past.
You also need to avoid alcohol if you have an alcohol related heart, liver, or other health problem.
If you drink alcohol, talk to your caregiver.
Cardiac rehabilitation (rehab) is a program that can help you feel better when you have heart failure. Cardiac rehab may decrease your risk of worsening heart failure. During cardiac rehab, you learn how to live a more heart-healthy lifestyle. You may also learn how to exercise safely to strengthen your muscles and heart.
Weigh yourself at the same time every morning. It is best to weigh yourself on the same scale, before eating, and after urinating. Try to wear the same type of clothing every time you weigh yourself. Record your weights, and the time you weighed yourself in a diary. Bring your diary to your follow-up visits with your caregiver. Weight gain can be a sign of extra fluid in your body.
You may need to limit the amount of sodium (salt) you eat to 2 to 3 grams each day. Check labels when shopping for food to find low sodium or no salt added foods. Some low sodium foods use potassium salts for flavor. Too much potassium can also cause health problems. Talk with your caregiver about what amount of sodium and potassium salt is okay for you.
Do not take any illegal street drugs, such as cocaine. Street drugs can make your heart failure symptoms worse. Talk to your caregiver if you use illegal drugs and need help to stop.
Exercise may help decrease your symptoms and improve your heart function. Exercise also
helps with weight control and keeps your muscles strong. A walking program or light aerobic exercise, 3
to 5 times each week, may help your heart failure. Always include warm-up and cool-down activity each
time you exercise. Never start an exercise program without talking with your caregiver.
you can plan the best exercise program for you. It is best to start slowly and do more as you get stronger.
If you feel more tired than usual the day after exercising, you may need to change your program.
You may need to limit the amount of liquid you drink each day. You may be told to drink only 2 liters (about 8 eight-ounce cups) or less of liquid daily. Follow your caregiver’s advice about how much liquid you should drink each day.
What to do if you get thirsty:
1. Drink fluids only when you are thirsty 2. Keep track of how much you drink by writing it down 3. Rinse your mouth with fluid 4. Suck on lemon wedge or ice chips 5. Freeze juice in ice cube tray 6. Use sugar free chewing gum or hard candies 7. Freeze grapes or strawberries 8. Drain liquid from vegetables and canned fruits 9. Don't forget to save some fluid for your medications 10. Humidifying room air may help
Smoking harms your body in many ways. Smoking can worsen you heart failure and cause
other heart disease, lung disease, and cancer. Quitting smoking will improve your health and the health of
those around you. Ask your caregiver for more information about how to stop smoking if you are having
Heart failure may cause you to have feelings of worry, fear, and sadness. You and those close to you may feel anxious and scared about your future. These feelings are normal. Learn ways to manage stress, such as deep breathing, meditation, and listening to music. You may choose to see a special caregiver to talk about your feelings. Your family and friends may also be a part of these meetings. Talking with a caregiver may help everyone understand your condition and care better.
Travel and outdoors:
Traveling to altitudes above 1500 meters (4921 feet) may increase your heart failure symptoms and should be avoided. Any outdoor conditions that can lead to shortness of breath should also be avoided. This includes very hot, and humid (moist) air, poor air quality (pollution), and inclement weather (storms).
Ask your caregiver if you should get vaccinated against the flu or pneumonia. The best time to get a flu shot is in October or November. Flu shots are good for one year. Pneumonia shots are good for five to six years. Ask your caregiver which vaccinations are right for you.
Maintain a healthy weight to decrease how hard your heart has to work. If you are overweight (weighing more than your caregiver suggest), ask your caregiver about a weight loss plan. If you have sleep apnea, losing weight may help you breathe better during sleep.
Additional Dietary Considerations
Because of your heart condition, it is very important that you keep track of what you eat and drink. Too much salt or fluid in your diet can stress the heart and lead to worsening of symptoms.
You should not consume more that 2 Liters, or 2000 ml (like the size of a big bottle of soda) of fluid in a day. This includes any form of liquid: including coffee, soup, ice cream, etc.
You should not consume more than 2 grams, or 2000 milligrams of salt (sodium) per day. Examples of foods with a high salt content include: chinese food, pizza, certain cheeses, salad dressings, cold cuts, canned soups, and any food served in a restaurant! See attached handouts regarding the salt content in processed foods and how to read a food label. Remember, if it comes in a box, can, or a bag, it has salt in it!
you should weigh youself at the same time in the morning.
you should ask yourself these questions:
1. Did you gain 2 or 3 pounds? 2. Are your feet swollen? 3. Is it hard to breathe when you lie flat on your back? 4. Do you have a new dry or loose cough? 5. Does your belly feel bloated? 6. Is it hard to breathe when you walk or get dressed? 7. Do you have chest pain? 8. Do you wake up in the middle of the night and find it difficult to breathe?
If you answer “yes” to any of these questions (especial y if your answer in the recent past has been “no”), please contact your doctor.
2014 / In Press 1. Uchida H, Suzuki T, Graff-Guerrero A, Mulsant BH, Pollock BG, Arenovich T, Rajji TK, Mamo DC. Therapeutic window for striatal dopamine D2/3 receptor occupancy in older patients with schizophrenia: a pilot PET study. Am J Geriatr 2. Fleischhacker WW, Uchida H. Critical review of antipsychotic polypharmacy in the treatment of schizophrenia. Int J Neuropsychopharm. (in pr
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