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Microsoft word - prostate hope clinical observation.doc

CLINICAL OBSERVATION
An All Natural Traditional Chinese
Herbal Formula for Prostate Care

Dr. Sherman Lai CMD, Dr. Ac., B. Sc. Oriental Healing Arts Research Inc. Guelph, ON, Canada Revised Edition May 2005 Abstract: This article is designed to provide clinical observational data on Prostate Hope™
to support patients suffering from rising prostate specific antigen (PSA) levels, as well as to
review the scientific literature supporting the evidence that Panax Ginseng, Ganoderma
lucidum,
and Scutellaria baicalensis, (while working synergistically with the sixteen other
ingredients in Prostate Hope™) help to repair both the immune and digestive systems as
well as cleanse and support the entire body. Sixty-eight patients participated in this clinical
observation study, all previously diagnosed with elevated PSA levels. There were no
controls for the patients diet and/or other forms of natural health product supplementation,
in addition to Prostate Hope™. The evaluation criterion was based on the decrease,
increase or no change in the PSA level. After the nine month observation period 51.5% of
the observation body had a PSA decrease greater than 20%. The results of our clinical
study, as well as the support from the scientific literature suggest that Prostate Hope™
could serve as an integrative therapeutic tool for prostate care.
Keywords: Prostate Hope™; Prostate Cancer; PC SPES; PSA reduction; Panax
Ginseng; Ganoderma lucidum; Scutellaria baicalensis

Prostate cancer is a very common
cancer, it is estimated that up to half of form of the disease. This is largely due to the fact that metastatic prostate cancer radiation; translating into a problem of is the most widespread cancer afflicting the metastatic form prior to their initial concern for the health care system due to scientific literature review detailing the findings that the nineteen ingredients in challenge that is of an alarming concern is the morbidity associated with prostate importantly, the rate at which the PSA is rising on top of an elevated PSA reading reducing PSA levels during their time of approaches for the treatment of prostate treatments have been clinically proven in fatigue, pain, swelling and hot flashes. cancer have been linked to diet, race and nature. All men 40 years or older should a quarter of the world’s population, but its philosophical and theoretical concepts intervention of prostate cancer (this test measures the level of PSA in the blood). prostate that is found in elevated levels in the blood of men with prostate cancer. (equal to or greater than 4), the next step result in blood stagnation, and so it is likely it is that the tumour will spread; cysts, abscesses, and tumours, which can potential of spreading. The prognosis of The six primary methods of treatment for cancer used by traditional Chinese medical
practitioners are as follows:

1
. Remove heat, dampness and toxicity
2. Removes stagnant blood and Qi
3. Re-balance the Qi
4. To soften and remove the mass
5. Remove the phlegm and moisture
6. Treat the cancer with poison
Proposed Theory of Prostate Hope™
ingredients that work synergistically to Patients
Hedyotis, Dyer’s Woad Leaf, Moutan, During 2001 to 2003, sixty eight patients Chrysanthemum, Scutellaria baicalensis, and Anemarrhena help to cleanse heat, Phellodendron bark, Dioscorea, Cornus, treatment and participated in the clinical Epidium, Lycium fruit, and Alisma help to tonify the kidneys, while Cornus and patient into the study was staggered as it depended on their arrival at the Centre of deficiencies. Licorice, Ganoderma lucidum, Poria, Panax Ginseng and Sang-Qi Ginseng all help to improve the two criteria to become eligible for entry flow of blood and Qi. Lastly, Hedyotis, Panax Ginseng and San-Qi Ginseng also tumour reduction. For the purpose of the Ganoderma lucidum, Scute barbata and hedyotis, evaluating their potential in integrative therapeutic aid for prostate Methods and Materials
Study Protocol
(equivalent to 10 capsules twice daily). There were no controls for the patient’s results of the patient’ PSA readings by their medical doctor. Figure 1 represents his research team on a monthly basis and to Prostate Hope™ during the course of completed every 3 months.
Figure 1: Representing the percentage of patients using Prostate Hope™ that
showed a decrease in their PSA level.

These results represent an efficacy rate took part in the study showed a decrease This clinical observation study outlines a survival is good. According to traditional Chinese medical theory for the treatment toxicity, therefore cleansing the body of clearly indicate that PSA level reduction In a clinical TCM setting, it is not our objective to refuse support for patients entering the facility nor to advise them considerations and logistical difficulty of Therefore, we were not able to conduct a cancer. A detailed list of the ingredients observation study, it is also difficult for treatments for cancer are relatively new, further investigation is warranted. It is also important to note however, that it is that unfortunately there is not one direct cancer, and that cancer therapy will have protocol, leaving further room for error. the patient during their battle with cancer an effect on the results. Due to patient and suffering felt during their fight with to lead a better lifestyle, with less pain, Panax Ginseng, Scutellaria baicalensis and Ganoderma lucidum. Recent studies nutrients, which in turn will aid in the because of their anti-cancer properties. Table 1 briefly outlines some of the anti- important role in Prostate Hope™ are:

Table 1: Brief description on three of the main ingredients in Prostate Hope™ that
have been shown through scientific studies to promote anti-cancer effects

Article
Tumor promotion is closely related to events such as increased activity and expression of ornithine decarboxylase (ODC) which plays an important role in cell proliferation as well as the increase in pro-inflammatory cytokines such as COX-2, which has been implicated in cancer development. Keum et al. demonstrated that Rg3, a major ginsenoside from Panax Ginseng, down regulates COX-2 and also has been studied to inhibit ODC activity. Based on the findings from this study, it is Rg3 that is responsible for Panax Ginseng anti-cancer effects. It has been documented that Ganoderma lucidum inhibits the cell motility of highly invasive breast and prostate cancer cells. Ganoderma lucidum demonstrates this ability through the following chain of events; it inhibits the transcription of AP-1 and NFκ-231, followed by the suppression of the uPA and uPAR expression reducing the migration of the breast and prostate cancer cells. Hence, halting the process of angiogenesis. Scutellaria baicalensis has been shown to have a strong dose dependent anti-cancer effect both in vivo and in vitro. The inhibition of cancer growth is not due to the induction of apoptosis; the results indicate it is due to the ability to cause G0 – G1 phase arrest. It should be noted that this herb selectively inhibits cancer cell growth and has been extensively studied to have no effect on non-cancerous cells. Therefore, the inhibition of tumor growth is not toxic to the peripheral blood lymphocytes. The study suggests that the synergistic effect among the nineteen ingredients can be integrated into any cancer treatment protocol for prostate care with 73 percent of cases showing a reduction in PSA levels. There are also many years of documented scientific literature further supporting our findings, suggesting that the ingredients in Prostate Hope™ have an anti-cancer effect. In conclusion, we believe that Prostate Hope™ has great potential to be used as an integrative approach for prostate cancer care. Reishi (Stem) Ganoderma lucidum
The stem of the Reishi plant is known to affect the liver, heart, spleen and lungs. Phellodrendron Bark Cortex
This bark exerts its affect on the kidneys Baikal Skullcap (Root) Scutellaria
Anemarrhena Anemarrhena
action is to clear heat, drain fire, enrich This herb is used to clear heat, drain fire yin, moisten dry conditions and generate fetus, sedate liver yang and it has also demonstrated an inhibitory effect against Dyer’s Woad (Leaf) Isatis Indigotica
The Dyer’s Woad Leaf affects the heart, febrile response after a Salmonella typhi It has been shown to clear heat, relieve Dioscorea Radix Dioscoreae Oppositae
Dioscorea affects the kidneys, lungs and Chrysanthemum Flos Chrysanthemi
traditional use to drain heat and relieve Cornus Fructus Corni Officinalis
Moutan Cotex Moutan Radicis
Cornus is known to affect the kidney and It has a wide range of actions, including excessive sweating, tonifies the liver and fire, invigorating blood, dispelling blood Rehmannia (Cooked) Radix
channels of the heart, kidney and liver. Hedyotis Herba Hedyotis Diffusae
Its main actions are to tonify and nourish Alisma Rhizoma Alismatis Orientalitis
Alisma exerts its effects on the kidneys Rabdosia (Leaf) Rabdosia Rubescens
urination and leach out dampness as well Poria (fushen) Sclerotium Poriae Cocos
In Chinese medicine, Poria is used for a variety of functions. Some actions of the the spleen, and calming the spirit. San-Qi Ginseng (Root) Panax
diuretic, a cardiotonic, an antibacterial and anticancer agent. It is also used to This root affects the liver, stomach and Licorice Root Glycyrrhizae Uralensis,
and tonifies the stomach. It is known to benefit the heart Qi and calm the spirit. Epimedium Epimedium Grandiflorum
coughing, clears heat, relieves toxicity, kidneys and fortify the yang. It is used uses including anti-inflammatory effects, use for asthmatics, gastrointestinal uses Lycium Fruit Lycium barbarun
Oriental Ginseng Panax Ginseng
Lycium fruit affects the liver, lungs and This herb exerts its effects the lungs and This herb nourishes and tonifies the liver It strongly tonifies and augments the Qi in the lungs. It strengthens the spleen After 6 weeks of taking Prostate Hope™ (I) 71-year-old male
After another 6 weeks of taking Prostate also agreed to have laser surgery to trim Hope™ at a dosage of 6 capsules 3 times After taking Prostate Hope™ at a dosage (III) 84-year-old male
(II) 71-year-old male
PSA levels were 9, 28, 51.3 respectively *He was prescribed Prostate Hope™ at a * He had a bit of a digestive adjustment *After 1 year his PSA began to rise up to in the first week of starting the protocol *His PSA had dropped from 53.7 to 47.6 After another 2 months of taking (V) 64-year-old male
He will continue to take Prostate Hope™ (IV) 73-year-old male
After 1 month of taking Prostate Hope™ Hope™ at a dosage of 7 capsules 3 times Hope™ at a dosage of 7 capsules 3 times After another 8 weeks of taking Prostate Hope™ at a dosage of 7 capsules 3 times Prostate Hope™ at a dosage of 3.5grams of June. He reported feeling really good (VI) 63-year-old male
2003, level was at 5.4 with Gleason level *He is very pleased with the results and will continue to take Prostate Hope at a Upon his next visit to the clinic, Dr. Lai Appendix C - Ingredient List of Dr. Lai’s ABC™ Further information can be found at www.bioherbalai.com or in the clinical observational study A Chinese Herbal Formula for the Intervention and Inhibition of Cancer Metastasis (Lai, S., 2004) Hedyotis Scutellaria baicalensis Corydalis Sargassum Dioscorea Vaccaria Persica Angelica Sinensis Bupleurum Salvia Root Dipsacus Citrus Seeds Melia Atractylodes Peony (red) Hornet Nest Ganoderma lucidum Astragalus 1. Allaby M., Oxford Dictionary of Plant 14. Heywood, V.H., Flowering Plants of the 5. Chen, J., Plant Foods & Nutritional 17. Keum Y., Han, S., Chun, K., Park, K., Nature’s Green Feast, Keats Publishing 20. Li Tiao-hua. Patterns and Treatment of 9. Fang Yao-zhong. Seven lectures on the 10. Fratkin, J.P., Chinese Herbal Patent 11. Furnell, D. Health from the Hedgerow, 23. Lu, H.C., The Chinese System of Using 12. Gao, D., The Encyclopedia of Chinese 24. Ma Ruo-shui. Theoretical Foundations Guiyang: Guizhou People’s Press, 1977. 34. Sliva, D., Labarrere, C., Slivova, V., lucidum suppresses motility of highly cells. Biochemical and Biophysical 27. Qin Bo-wei. Medical Lecture Notes of Research Communications. 298:603-12 35. Tanaka, T., Tanaka’s Encyclopedia of Medical Reference for Clinical Patterns. 36. Teeguarden, R., Chinese Tonic Herbs, 37. Tull, D., A Practical Guide to Edible 30. Reis, S.V., Frank J. Lipp. Jr. New Plant 38. Wit, H.C.D. de. Plants of the World, 39. Zhai Ming-yi. Clinical Foundations of 40. Zhang, D., Fei, J., Xue, Li, Jiang, S., Yi, Synthesis by Scutellaria Baicalensis.

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