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Form 34qr asperger-june2009.pub

Note: The data below are based on cases identified as “Asperger Syndrome” N=1,366
PARENT RATINGS OF BEHAVIORAL EFFECTS OF BIOMEDICAL INTERVENTIONS
Autism Research Institute ● 4182 Adams Avenue ● San Diego, CA 92116
The parents of autistic children represent a vast and important reservoir of information on the benefits—and adverse effects— of the large variety of drugs and other interventions that have been tried with their children. Since 1967 the Autism Research Institute has been collecting parent ratings of the usefulness of the many interventions tried on their autistic children. The following data have been collected from 1,366 parents who have completed our questionnaires designed to collect such information. For the purposes of the present table, the parents responses on a six-point scale have been combined into three categories: “made worse” (ratings 1 and 2), “no effect” (ratings 3 and 4), and “made better” (ratings 5 and 6). The “Better:Worse” column gives the number of children who “Got Better” for each one who “Got Worse.” Parent Ratings
Parent Ratings
Parent Ratings
Got No Got Better: No. of
Got No Got Better: No. of
Got No Got Better: No. of
WorseA Effect Better Worse CasesB DRUGS WorseA Effect Better Worse CasesB
DRUGS WorseA Effect Better Worse CasesB
53% 27% 1.3:1
DilantinD
Prolixin
25% 34% 0.8:1
Behavior
1.2:1 185
Amphetamine 32%
28% 40% 1.2:1
Seizures
Risperidal
2.6:1 210
Anafranil
46% 39% 2.6:1
Fenfluramine 13% 75% 13% 1.1:1 8
1.0:1 413
Antibiotics
43% 22% 0.6:1
AntifungalsC
Secretin
Intravenous 13%
Diflucan
35% 60% 11:1
KlonapinD
Transderm. 0%
Nystatin
43% 50% 7.5:1
Behavior
Stelazine
44% 24% 0.8:1
Seizures
Steroids
Benadryl
45% 24% 0.8:1
Beta Blocker 8%
54% 38% 5.0:1
TegretolD
46% 34% 1.7:1
Mellaril
Behavior
MysolineD
Seizures
50% 17% 0.5:1
Behavior
Thorazine
Clonidine
38% 40% 1.8:1
Seizures
Tofranil
Clozapine
48% 22% 0.8:1
Naltrexone
Cogentin
54% 23% 1.0:1
47% 18% 0.5:1
Naltreone
ZarontinD
DepakeneD
Behavior
Behavior
42% 34% 1.4:1
Phenobarb.D
Seizures
Seizures
48% 39% 3.0:1
Behavior
1.2:1 133
Desipramine 20%
47% 33% 1.7:1
Seizures
BIOMEDICAL/
Parent Ratings
BIOMEDICAL/
Parent Ratings
NON-DRUG/
Got No Got Better: No. of
NON-DRUG/
Got No Got Better: No. of
SUPPLEMENTS WorseA Effect Better Worse CasesB
SUPPLEMENTS
WorseA Effect Better Worse CasesB
CalciumE
Transfer Factor
61% 33% 6.0:1
Cod Liver Oil
Vitamin A
61% 34% 6.7:1
Cod Liver Oil with
Vitamin B3
44% 50% 7.8:1
Bethanecol
Vit. B6/Mag.
44% 52% 13:1
Colostrum
Vitamin B12 (oral) 5%
40% 55% 12:1
Detox. (Chelation)C
Vitamin C
49% 48% 14:1
Digestive Enzymes
39% 58% 15:1
Fatty Acids
SPECIAL DIETS
Candida Diet
34% 64% 30:1
Folic Acid
Feingold Diet
35% 64% 70:1
Food Allergy Trtmnt 4% 34%
Gluten- /Casein-
25% 72% 32:1
Hyperbaric Oxygen
Free Diet
Low Oxalate Diet
Magnesium
49% 49% 27:1
Melatonin
Chocolate
Methyl B12 (nasal)
Removed Eggs
58% 38% 9.0:1
Methyl B12 (subcut.) 12% 25%
Removed Milk
39% 59% 28:1
MT Promoter
Products/Dairy
P5P (Vit. B6)
Removed Sugar
46% 52% 18:1
Removed Wheat
36% 62% 40:1
Rotation Diet
37% 61% 23:1
St. Johns Wort
Specific Carbo-
21% 74% 18:1
hydrate Diet
A. “Worse” refers only to worse behavior. Drugs, but not nutrients, typically also cause physical problems if used long-term. B. No. of cases is cumulative over several decades, so does not reflect current usage levels (e.g., Haldol is now seldom used). C. Antifungal drugs and chelation are used selectively, where evidence indicates they are needed. D. Seizure drugs: top line behavior effects, bottom line effects on seizures. E. Calcium effects are not due to dairy-free diet; statistics are similar for milk drinkers and non-milk drinkers.

Source: http://www.ariconference.com/asperger.pdf

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